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Revvity
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Image Search Results
Journal: Neuropsychopharmacology
Article Title: GABA A and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia
doi: 10.1038/s41386-021-01213-0
Figure Lengend Snippet: A A mixed three-way ANOVA of [ 3 H]-Ro15-4513 binding ( n = 14–16/group) showed a main effect of group (MAM vs. SAL; F (1,58) = 8.410, p = 0.005) but no main effect of condition (DZP vs. SAL; F (1,58) = 2.303, p = 0.135). C A mixed three-way ANOVA of [ 3 H]-flumazenil binding ( n = 13–18/group) showed no main effects ( p > 0.05). E A mixed three-way ANOVA of [ 3 H]-MK801 binding ( n = 15–20/group) showed a ROI × group interaction ( F (2,130) = 4.117, p = 0.019) and follow-up analysis revealed a MAM vs. SAL difference in the dHipp CA1 ( p = 0.001, q = 0.030). Pseudo-color representative autoradiographs of ( B ) [ 3 H]-Ro15-451 3 binding, ( D ) [ 3 H]-flumazenil binding, and ( F ) [ 3 H]-MK801 binding. Data are displayed as mean ± SEM.
Article Snippet: To quantify α5GABA A R density, we used [ 3
Techniques: Binding Assay
Journal: Neuropsychopharmacology
Article Title: GABA A and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia
doi: 10.1038/s41386-021-01213-0
Figure Lengend Snippet: A – C [ 3 H]-Ro15-4513 binding was inversely correlated with amphetamine-induced hyperlocomotion. D [ 3 H]-MK801 binding was positively correlated with amphetamine-induced hyperlocomotion. E , F [ 3 H]-Ro15-4513 binding was positively correlated with time spent in open arms, but correlation failed to reach significance with entries into open arms of the EPM.
Article Snippet: To quantify α5GABA A R density, we used [ 3
Techniques: Binding Assay